Research

My research develops and evaluates methods and frameworks to improve the safety, security, and ethical reliability of AI systems, with a particular focus on large language models. I study how these systems behave in sensitive, high-risk settings such as healthcare, and design approaches to systematically assess and mitigate the associated risks. Alongside the technical work, I gather empirical evidence to help policymakers and other non-technical stakeholders make informed decisions that reduce algorithmic harm.

Responsible AI

Responsible AI

Governance, evaluation, and accountability in deployed AI systems.

Safety, Security & Robustness

Safety, Security & Robustness

Failure modes, stress testing, and adversarial evaluation of machine learning models.

Natural Language Processing

Natural Language Processing

Modeling and evaluation of large language systems.

Affective Computing

Affective Computing

Understanding emotion, wellbeing, and human experience from data.

Stress Testing and Failure Analysis of Large Language Models

This line of research focuses on developing methods for stress testing large language models to systematically identify failure modes, including jailbreak vulnerabilities, unsafe outputs, and robustness breakdowns under distribution shift. The work emphasizes evaluation frameworks and adversarial testing approaches for characterizing model behavior in high-risk or deployment-relevant settings.

Responsible AI

Developed through close collaboration with interdisciplinary teams at NU’s Responsible AI Practice and industry partners, this work spans domains such as gaming, healthcare, and finance. Spanning domains such as gaming, healthcare, and finance, the work translates technical evaluation, monitoring, and guardrail methods into applied settings. Research outputs are informed by real-world deployment constraints and emphasize issues that emerge over the system lifecycle.

AI Systems and Suicide

This work examines how AI systems interact with suicide-related content, focusing on system behavior, responses, safeguards, and evaluation. Ongoing work includes (i) understanding how suicide is expressed through language and emotional expression, and (ii) identifying the medical and sociodemographic contexts that drive suicide risk. These findings are used as evidence to inform policy and deployment decisions involving AI systems.

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AI Systems and Suicide
Selected publications
Ethics Guidelines for AI-Based Suicide Prevention ToolPhilosophy of AI: The State of the Art · 2026‘For Argument’s Sake, Show Me How to Harm Myself!’: Jailbreaking LLMs in Suicide and Self-Harm ContextsIEEE ISTAS · 2025Lexicography Saves Lives (LSL): Automatically translating suicide-related languageCOLING · 2025The first multilingual model for the detection of suicide textsScaling Up Multilingual & Multicultural Evaluation · 2025Automatically extracting social determinants of health for suicide: a narrative literature reviewnpj Mental Health Research · 2024All models are wrong, but some are deadly: Inconsistencies in emotion detection in suicide-related tweetsNLP for Positive Impact · 2024Is it safe to machine translate suicide-related language from English to Galician?PROPOR · 2024An example of (too much) hyper-parameter tuning in suicide ideation detectionICWSM · 2023Classifying suicide-related content and emotions on Twitter using graph convolutional neural networksIEEE Trans. Affective Computing · 2022Automatic identification of suicide notes with a transformer-based deep learning modelInternet Interventions · 2021Hierarchical multiscale recurrent neural networks for detecting suicide notesIEEE Trans. Affective Computing · 2021Dilated LSTM with ranked units for Classification of Suicide NotesAI for Social Good @ NeurIPS · 2019Dilated LSTM with attention for classification of suicide notesLOUHI · 2019Automatic identification of suicide notes from linguistic and sentiment featuresSIGHUM · 2016

Building an Actionable Framework to Responsible AI Integration in Clinical and Public Health Contexts

Building on the AI Ethics Box, this work adapts bioethical principles to healthcare settings and links them to concrete technical methods for evaluation, governance, and post-deployment monitoring. The framework addresses the gap between high-level ethical guidance and operational decision-making in clinical and public health contexts. It is refined through interdisciplinary collaboration and stakeholder co-design, supporting practical use by clinicians, health system leaders, and developers in real-world AI deployment.

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Building an Actionable Framework for Responsible AI Integration in Clinical and Public Health Contexts
Funding

RAI4MH: Responsible AI for Mental Health Initiative

RAI4MH is an international partnership developing evidence-based guidance for the responsible use of AI in mental health contexts. As the U.S. lead, I contribute to coordinating interdisciplinary collaboration across computer science, mental health, ethics, and policy. Key outputs include white papers that synthesize international expert consensus and contribute directly to policy discussions, including a POSTnote for the UK Parliament on responsible AI in mental health.

SHAPE-AI: Smart Health Analytics and Predictive Engagement with AI

This work studies how AI learning companions intersect with student mental health, cognition, and academic outcomes. It integrates multimodal data including biometric signals (sleep, activity, physiology), academic performance, and patterns of AI use to model wellbeing and learning trajectories. The study examines AI use as a digital phenotype of academic engagement and supports evidence-based guidance for intervention design and responsible AI deployment in higher education.

Ethics Guidelines for AI-Based Suicide Prevention Tool
LH Ihle, AM Schoene · 2026 · Philosophy of AI: The State of the Art
Responsible AI in mental healthcare: policy directions and stakeholder insights
AM Schoene, R Mestre, SE Middleton, A Lapedriza, et al. · 2026 · Frontiers in Public Health
Lexicography Saves Lives (LSL): Automatically translating suicide-related language
AM Schoene, JE Ortega, RJ Zevallos, LH Ihle · 2025 · COLING
The first multilingual model for the detection of suicide texts
RJ Zevallos, AM Schoene, JE Ortega · 2025 · Scaling Up Multilingual & Multicultural Evaluation
Automatically extracting social determinants of health for suicide: a narrative literature review
AM Schoene, S Garverich, I Ibrahim, S Shah, B Irving, CC Dacso · 2024 · npj Mental Health Research
MEANT: Multimodal Encoder for Antecedent Information
B Irving, AM Schoene · 2024 · EMNLP
All models are wrong, but some are deadly: Inconsistencies in emotion detection in suicide-related tweets
AM Schoene, R Ramachandranpillai, T Lazovich, RA Baeza-Yates · 2024 · NLP for Positive Impact
Why the gaming industry needs responsible AI
C Canca, LH Ihle, AM Schoene · 2024 · ACM Games: Research and Practice
An example of (too much) hyper-parameter tuning in suicide ideation detection
AM Schoene, J Ortega, S Amir, K Church · 2023 · ICWSM
Emerging trends: Unfair, biased, addictive, dangerous, deadly, and insanely profitable
K Church, A Schoene, JE Ortega, R Chandrasekar, V Kordoni · 2023 · Natural Language Engineering
Classifying suicide-related content and emotions on Twitter using graph convolutional neural networks
AM Schoene, L Bojanić, MQ Nghiem, IM Hunt, S Ananiadou · 2022 · IEEE Trans. Affective Computing
A narrative literature review of natural language processing applied to the occupational exposome
AM Schoene, I Basinas, M Van Tongeren, S Ananiadou · 2022 · IJERPH
Natural language processing applied to mental illness detection: a narrative review
T Zhang, AM Schoene, S Ji, S Ananiadou · 2022 · npj Digital Medicine
Exposome methods in occupational epidemiology: Use of text mining for developing Job Exposure Matrices
M van Tongeren, C Ge, E Kuijpers, S Ananiadou, et al. · 2021 · Occupational and Environmental Medicine
NERO: a biomedical named-entity recognition ontology with a large, annotated corpus
K Wang, R Stevens, H Alachram, Y Li, L Soldatova, R King, S Ananiadou, et al. · 2021 · npj Systems Biology and Applications
Automatic identification of suicide notes with a transformer-based deep learning model
T Zhang, AM Schoene, S Ananiadou · 2021 · Internet Interventions
A divide-and-conquer approach to neural natural language generation from structured data
N Dethlefs, A Schoene, H Cuayáhuitl · 2021 · Neurocomputing
Hierarchical multiscale recurrent neural networks for detecting suicide notes
AM Schoene, AP Turner, G De Mel, N Dethlefs · 2021 · IEEE Trans. Affective Computing
Hybrid approaches to fine-grained emotion detection in social media data
AM Schoene · 2020 · AAAI/SIGAI Doctoral Consortium
Improving the Transparency of Deep Neural Networks using Artificial Epigenetic Molecules
G Lacey, AM Schoene, N Dethlefs, AP Turner · 2020 · IJCCI
Dilated LSTM with ranked units for Classification of Suicide Notes
AM Schoene, AP Turner, N Dethlefs · 2019 · AI for Social Good @ NeurIPS
Dilated LSTM with attention for classification of suicide notes
AM Schoene, G Lacey, AP Turner, N Dethlefs · 2019 · LOUHI
Modularity Within Artificial Gene Regulatory Networks
G Lacey, A Schoene, N Dethlefs, A Turner · 2019 · IEEE CEC
Evolutionary constraint in artificial gene regulatory networks
AP Turner, G Lacey, A Schoene, N Dethlefs · 2018 · UKCI

Data access: Available upon request